Is it fine to take antacids or indigestion remedies at the same time as stimulant medication?

ADHD
medication
antacids
medicine interactions
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tiny_task_marathon
Is it fine to take antacids or indigestion remedies at the same time as stimulant medication?
2026-08-25 09:14
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James White
James White
Nurse Practitioner
It depends on which stimulant and which indigestion remedy you mean. They aren't universally safe to take together. • Amphetamine stimulants (such as Adderall, lisdexamfetamine): antacids that raise stomach pH, particularly alkaline products containing sodium bicarbonate or calcium carbonate, can increase amphetamine absorption/exposure and is a specific contra indication. • Acid-reducing medicines such as PPIs (omeprazole, etc.) and H2 blockers can also affect drugs whose absorption depends on stomach acidity, so the specific stimulant matters. • Methylphenidate (Ritalin, Concerta, etc.) has different interaction considerations, so the answer isn't the same as for amphetamines. So I wouldn't assume that taking an antacid at exactly the same time is fine without knowing the medications.

*Disclaimer: Responses provided by Providers in this Community do not constitute medical advice. No physician–patient relationship is created through these responses. For personal medical decisions, a formal clinical consultation is required.

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